Vertex Pharmaceuticals (VRTX) closed at $468.09, up 0.94%, outperforming the S&P 500's 0.38% gain. Despite a 0.42% decline over the past month, analysts anticipate a revenue increase to $2.77 billion for the upcoming earnings report, although EPS is projected to drop by 3.1%. Currently, VRTX holds a Zacks Rank of #3 (Hold) with a high Forward P/E ratio of 934.65, indicating a premium valuation compared to its industry.